Jack McBrayer Is Set to Make Drama-Filled Guest Appearance onGrey’s Anatomy: See the Trailer!

Mar. 15, 2025

Jack McBrayeris coming to Grey Sloan Memorial.In the trailer for the Oct. 10 episode ofGrey’s Anatomy, the30 Rockalum, 51, plays a patient who is at the hospital for a kidney transplant.As they prepare to operate, Simone Griffin (Alexis Floyd) introduces the patient as “Tom Costello, 33. Kidney transplant without general anesthesia.““What are the benefits of an awake surgery?” asks Nick Marsh (Scott Speedman) as the interns appear somewhat stumped.While laying on the operating table, Tom questions, “Is he prepared?”Jack McBrayer attends Netflix’s “Unfrosted” premiere at The Egyptian Theatre on April 30, 2024 in Los Angeles, California.Charley Gallay/GettyThe actor is best known for playing NBC page Kenneth Parcell on30 Rock, which ran for seven seasons from 2006 to 2013. In 2009, he received an Emmy nomination for outstanding supporting actor in a comedy series for his performance.He also voiced Fix-it Felix Jr. inWreck-it Ralphand Wander in the Disney XD series,Wander Over Yonder, and created, executive produced and appeared inHello Jack! The Kindness Show.Elsewhere in the trailer, Meredith Grey (Ellen Pompeo) prepares to do a liver biopsy on Catherine Fox (Debbie Allen) and tells Nick that “her cancer may have spread.““Richard doesn’t know, does he?” he replies.During the procedure, there appears to be a complication as machines beep off. Meredith acknowledges, “She might never wake up for this. Richard needs to know.“On theseason 21 premiereof the hit ABC medical drama, Meredith discovered Catherine’s cancer was progressing and she needed immediate treatment, but Catherine wanted her to keep secret and advised to “keep your mouth shut. She planned to keep her son Jackson Avery (Jesse Williams) and husband Richard Webber (James Pickens Jr.) in the dark about her condition.Meredith then questioned what happened if she didn’t comply and Catherine replied that she would prevent Teddy Altman (Kim Raver), Amelia Shepherd (Caterina Scorsone) and Owen Hunt (Kevin McKidd) from getting their jobs back after they were fired for their involvement in Meredith’s secret research.“You’re threatening me over your health,” Meredith fired back and Catherine responded, “I’ve blackmailed people over far less.”Debbie Allen on “Grey’s Anatomy”.Disney/Anne Marie FoxAllen, 74, told previously PEOPLE that there aremore challenges aheadfor Catherine on this season of the ABC medical drama.“Ms. Catherine’s going to go through some real challenges with her health and understanding of her role in the leadership in that medical world that she lives in,” she teased.The actress noted that the show is “so dynamic,” adding, “I wish I could tell you, but I’m telling you, week to week to week, we laugh out loud, we cry. We’re going to make the world care, which is whatGrey’s Anatomyhas always been.”“We are following the footprint that [creator]Shonda Rhimeshas left us,” she continued. “And we have an incredible showrunner now, Meg Marinis…She is amazing. So collaborative, but also can see where we’re going to go, and we’re all there.”Never miss a story — sign up forPEOPLE’s free daily newsletterto stay up-to-date on the best of what PEOPLE has to offer, from juicy celebrity news to compelling human interest stories.Grey’s Anatomyairs Thursdays at 10 p.m. ET on ABC.

Jack McBrayeris coming to Grey Sloan Memorial.

In the trailer for the Oct. 10 episode ofGrey’s Anatomy, the30 Rockalum, 51, plays a patient who is at the hospital for a kidney transplant.

As they prepare to operate, Simone Griffin (Alexis Floyd) introduces the patient as “Tom Costello, 33. Kidney transplant without general anesthesia.”

“What are the benefits of an awake surgery?” asks Nick Marsh (Scott Speedman) as the interns appear somewhat stumped.

While laying on the operating table, Tom questions, “Is he prepared?”

Jack McBrayer attends Netflix’s “Unfrosted” premiere at The Egyptian Theatre on April 30, 2024 in Los Angeles, California.Charley Gallay/Getty

Charley Gallay/Getty

The actor is best known for playing NBC page Kenneth Parcell on30 Rock, which ran for seven seasons from 2006 to 2013. In 2009, he received an Emmy nomination for outstanding supporting actor in a comedy series for his performance.

He also voiced Fix-it Felix Jr. inWreck-it Ralphand Wander in the Disney XD series,Wander Over Yonder, and created, executive produced and appeared inHello Jack! The Kindness Show.

Elsewhere in the trailer, Meredith Grey (Ellen Pompeo) prepares to do a liver biopsy on Catherine Fox (Debbie Allen) and tells Nick that “her cancer may have spread.”

“Richard doesn’t know, does he?” he replies.

During the procedure, there appears to be a complication as machines beep off. Meredith acknowledges, “She might never wake up for this. Richard needs to know.”

On theseason 21 premiereof the hit ABC medical drama, Meredith discovered Catherine’s cancer was progressing and she needed immediate treatment, but Catherine wanted her to keep secret and advised to “keep your mouth shut. She planned to keep her son Jackson Avery (Jesse Williams) and husband Richard Webber (James Pickens Jr.) in the dark about her condition.

Meredith then questioned what happened if she didn’t comply and Catherine replied that she would prevent Teddy Altman (Kim Raver), Amelia Shepherd (Caterina Scorsone) and Owen Hunt (Kevin McKidd) from getting their jobs back after they were fired for their involvement in Meredith’s secret research.

“You’re threatening me over your health,” Meredith fired back and Catherine responded, “I’ve blackmailed people over far less.”

Debbie Allen on “Grey’s Anatomy”.Disney/Anne Marie Fox

Disney/Anne Marie Fox

Allen, 74, told previously PEOPLE that there aremore challenges aheadfor Catherine on this season of the ABC medical drama.

“Ms. Catherine’s going to go through some real challenges with her health and understanding of her role in the leadership in that medical world that she lives in,” she teased.

The actress noted that the show is “so dynamic,” adding, “I wish I could tell you, but I’m telling you, week to week to week, we laugh out loud, we cry. We’re going to make the world care, which is whatGrey’s Anatomyhas always been.”

“We are following the footprint that [creator]Shonda Rhimeshas left us,” she continued. “And we have an incredible showrunner now, Meg Marinis…She is amazing. So collaborative, but also can see where we’re going to go, and we’re all there.”

Never miss a story — sign up forPEOPLE’s free daily newsletterto stay up-to-date on the best of what PEOPLE has to offer, from juicy celebrity news to compelling human interest stories.

Grey’s Anatomyairs Thursdays at 10 p.m. ET on ABC.

source: people.com